US 12,263,144 B2
Methods of treating IgA nephropathy with thiol-containing molecules
Jing Jin, Chicago, IL (US)
Assigned to Accubit LLC—Biotechnology, Chicago, IL (US)
Filed by Accubit LLC—Biotechnology, Chicago, IL (US)
Filed on Oct. 13, 2021, as Appl. No. 17/500,625.
Claims priority of provisional application 63/090,902, filed on Oct. 13, 2020.
Prior Publication US 2022/0110894 A1, Apr. 14, 2022
Int. Cl. A61K 31/145 (2006.01); A61P 13/12 (2006.01); G01N 33/68 (2006.01)
CPC A61K 31/145 (2013.01) [G01N 33/6854 (2013.01)] 12 Claims
 
1. A method of treating renal IgA deposition in mammals, the method comprising administering a therapeutically effective amount of a thiol-containing molecule, or a pharmaceutically acceptable salt thereof, to a mammal suffering from or at risk of having IgA nephropathy, wherein the thiol-containing molecule is selected from the group consisting of cysteamine, 2-[(3-aminopropyl) amino] ethanethiol, and N-acetylcysteine.