| CPC A61F 2/06 (2013.01) [A61F 2/0077 (2013.01); A61L 31/04 (2013.01); A61L 31/146 (2013.01); A61F 2002/0081 (2013.01); A61F 2210/0076 (2013.01)] | 20 Claims |

|
1. A method for reducing or preventing stenosis caused by neointimal hyperplasia within or near either end of an implanted vascular graft, the method comprising: connecting a vascular graft to one or more native blood vessels to provide the implanted vascular graft in tissue, wherein the vascular graft has a tissue-interface layer having textured microporous surface that reduces constriction from the tissue response to the implanted vascular graft to a degree that reduces neointimal hyperplasia, and wherein the tissue-interface layer comprises interconnected pores that are larger than 20 microns and smaller than 200 microns, and where adjacent pores have inter-pore openings of larger than 5 microns and smaller than 50 microns.
|