US 12,263,048 B2
Biopsy site marker
Estefania Alvarez, Watertown, MA (US); Adam Kozak, Marlborough, MA (US); Jaimee Robertson, Marlborough, MA (US); and Stephen Spiegelberg, Marlborough, MA (US)
Assigned to HOLOGIC, INC., Marlborough, MA (US)
Filed by HOLOGIC, INC, Marlborough, MA (US)
Filed on Dec. 4, 2023, as Appl. No. 18/528,055.
Application 18/528,055 is a continuation of application No. 16/463,023, granted, now 11,877,898, previously published as PCT/US2017/053782, filed on Sep. 27, 2017.
Claims priority of provisional application 62/425,953, filed on Nov. 23, 2016.
Prior Publication US 2024/0173097 A1, May 30, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 90/00 (2016.01); A61B 10/00 (2006.01); A61B 17/00 (2006.01)
CPC A61B 90/39 (2016.02) [A61B 10/0041 (2013.01); A61B 2017/00796 (2013.01); A61B 2017/00845 (2013.01); A61B 2017/00853 (2013.01); A61B 2017/00867 (2013.01); A61B 2017/00898 (2013.01); A61B 2090/3904 (2016.02); A61B 2090/3908 (2016.02); A61B 2090/3925 (2016.02); A61B 2090/3954 (2016.02); A61B 2090/3966 (2016.02); A61B 2090/3987 (2016.02); A61B 2090/3995 (2016.02)] 20 Claims
OG exemplary drawing
 
1. A detectable marker for implantation in a targeted site, the marker comprising:
an outer portion formed by polymeric threads and defining an interior region, wherein, upon implantation in the targeted site, the outer portion is configured to transition from a collapsed shape to an expanded shape, the expanded shape being different than the collapsed shape and defining a hyperechoic region of the marker; and a hydrogel body contained within the interior region of the outer portion of the marker, the hydrogel body being configured to transition between a pre-deployment configuration and a post-deployment configuration when exposed to a fluid, and to provide a hypoechoic region of the marker,
wherein, in the post-deployment configuration, the hydrogel body swells to a final, fully expanded size, and
wherein, when the hydrogel body is in the final, fully expanded size, the hydrogel body fills less than an entirety of the interior region of the expanded shape of the outer portion of the marker.