| CPC A61B 8/065 (2013.01) [A61B 8/4416 (2013.01); A61B 8/488 (2013.01)] | 15 Claims |
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1. A system adapted to determine an estimate of at least one hemodynamic parameter of a subject, the system comprising an ECG sensor, a PPG sensor, an ultrasound device, and a controller, wherein the controller is adapted to:
receive, from the ECG sensor, a data input indicative of a heart blood ejection event;
receive, from the PPG sensor, a data input indicative of arrival of a corresponding pulse wave at a pre-determined location along a respective arterial path;
receive, from the ultrasound device, a data input indicative of an arterial blood flow measurement in at least one arterial path of the subject, the arterial path being a peripheral arterial path, or a central arterial path;
obtain for each of the peripheral arterial path and the central arterial path a measure indicative of a time difference, ΔT, between the heart blood ejection event and the arrival of the corresponding pulse wave at the pre-determined location along the respective arterial path, as a result of blood flow from the heart to the location;
provide the arterial blood flow measurement for the at least one arterial path, and the measures indicative of the time difference, ΔT, for both the central and peripheral arterial path, or parameters derived therefrom, as inputs to a pre-determined transfer function, and wherein the transfer function is adapted to generate the estimate for the at least one hemodynamic parameter based on the inputs and a pre-determined functional relationship between the inputs and the at least one hemodynamic parameter; and
generate a data output indicative of the estimate of the at least one hemodynamic parameter.
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