US 12,262,984 B2
Systems and methods for spin labeling in magnetic resonance imaging
David Alsop, Newton, MA (US); and Manuel Taso, Boston, MA (US)
Assigned to BETH ISRAEL DEACONESS MEDICAL CENTER, INC., Boston, MA (US)
Appl. No. 17/756,366
Filed by Beth Israel Deaconess Medical Center, Inc., Boston, MA (US)
PCT Filed Nov. 25, 2020, PCT No. PCT/US2020/062256
§ 371(c)(1), (2) Date May 24, 2022,
PCT Pub. No. WO2021/108573, PCT Pub. Date Jun. 3, 2021.
Claims priority of provisional application 62/940,555, filed on Nov. 26, 2019.
Prior Publication US 2023/0033905 A1, Feb. 2, 2023
Int. Cl. A61B 5/055 (2006.01); A61B 5/026 (2006.01); G01R 33/563 (2006.01)
CPC A61B 5/055 (2013.01) [G01R 33/56366 (2013.01); A61B 5/0263 (2013.01)] 25 Claims
OG exemplary drawing
 
10. A method for producing an image of a subject using a magnetic resonance imaging (MRI) system, the steps comprising:
a) determining a slice profile for a spin labeling imaging pulse sequence;
b) determining a ratio of a radio frequency (RF) slice selection gradient to a time averaged gradient for the spin labeling perfusion imaging sequence;
c) reducing the ratio so that a plurality of aliased labeling planes are within the slice profile;
d) acquiring image data of the subject from regions downstream of the plurality of aliased labeling planes using a pulse sequence designed from steps a) through c); and
e) reconstructing an image of the subject from the image data acquired at step d).