CPC H05K 3/321 (2013.01) [A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/1459 (2013.01); A61B 5/1473 (2013.01); A61B 5/14865 (2013.01); A61B 5/1495 (2013.01); A61B 5/6801 (2013.01); A61B 5/6849 (2013.01); A61M 5/14244 (2013.01); A61M 5/14276 (2013.01); A61M 5/1723 (2013.01); A61M 5/20 (2013.01); A61M 11/00 (2013.01); A61M 15/0065 (2013.01); A61M 15/0068 (2014.02); A61M 15/008 (2014.02); A61M 15/0083 (2014.02); A61M 35/00 (2013.01); G01N 27/3273 (2013.01); G01N 27/3274 (2013.01); G01N 33/66 (2013.01); G16H 20/17 (2018.01); G16H 40/63 (2018.01); A61B 5/0031 (2013.01); A61B 2560/0468 (2013.01); A61B 2562/043 (2013.01); A61B 2562/08 (2013.01); A61B 2562/085 (2013.01); A61B 2562/12 (2013.01); A61B 2562/125 (2013.01); A61B 2562/16 (2013.01); A61M 5/003 (2013.01); A61M 2005/14296 (2013.01); A61M 5/178 (2013.01); A61M 5/30 (2013.01); A61M 15/00 (2013.01); A61M 2205/3569 (2013.01); A61M 2205/50 (2013.01); A61M 2205/502 (2013.01); A61M 2205/52 (2013.01); A61M 2205/581 (2013.01); A61M 2205/582 (2013.01); A61M 2205/587 (2013.01); A61M 2205/8206 (2013.01); A61M 2230/201 (2013.01); Y10T 29/49169 (2015.01)] | 20 Claims |
1. A method of making an on-skin wearable device, the method comprising:
assembling electronic circuitry into an internal volume of a housing, wherein the electronic circuitry is configured for (1) detecting signals generated from an electrochemical reaction under the skin of a subject at a working electrode of an analyte sensor, and (2) wirelessly transmitting data derived from the detected signals outside of the housing for processing and/or display by a separate device;
after assembling the electronic circuitry into the internal volume of the housing, attaching a proximal portion of the analyte sensor to an external electrical interface coupled to the electronic circuitry such that the electronic circuitry becomes connected to the analyte sensor to receive signals therefrom without opening the housing, wherein the external electrical interface is formed in a recess located in an external bottom surface of the housing, the external bottom surface configured to directly contact a patch for coupling the housing to the skin of the subject; and
dispensing a curable liquid into the recess to seal the attachment of the proximal portion of the analyte sensor to the external electrical interface.
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