US 11,939,444 B2
Modified polymer film surfaces for single-use bioreactor bags and biocontainment and methods of forming same
Peter D. Gabriele, Frisco, TX (US); Jeremy J. Harris, Doylestown, PA (US); Scott Radzinski, Gilbertsville, PA (US); Brian Ginn, Harleysville, PA (US); and Ryan R. Smalley, Lansdale, PA (US)
Assigned to THE SECANT GROUP, LLC, Telford, PA (US)
Filed by THE SECANT GROUP, LLC, Telford, PA (US)
Filed on Apr. 9, 2021, as Appl. No. 17/226,718.
Claims priority of provisional application 63/007,523, filed on Apr. 9, 2020.
Prior Publication US 2021/0317278 A1, Oct. 14, 2021
Int. Cl. C08J 7/12 (2006.01); B05D 3/10 (2006.01); B05D 7/04 (2006.01); C08J 7/04 (2020.01); C12M 1/00 (2006.01)
CPC C08J 7/12 (2013.01) [B05D 3/101 (2013.01); B05D 7/04 (2013.01); C08J 7/0427 (2020.01); C12M 23/14 (2013.01); C12M 23/28 (2013.01); B05D 2201/02 (2013.01); B05D 2350/30 (2013.01); B05D 2508/00 (2013.01); C08J 2331/04 (2013.01); C08J 2467/00 (2013.01)] 19 Claims
OG exemplary drawing
 
7. A single-use bioreactor bag comprising a polymer film comprising:
a base layer of a first composition of poly(ethylene-vinyl acetate);
a surface layer at a surface of the base layer, the surface layer comprising surface hydroxy groups converted from acetate groups of the poly(ethylene-vinyl acetate); and
a coating layer of a second composition of a copolymer of glycerol, sebacic acid, and citric acid;
wherein the second composition is attached to the surface layer by ester bonds between carboxyl groups of the copolymer of glycerol, sebacic acid, and citric acid and the hydroxy groups of the surface layer.