US 11,939,308 B2
Biphenyl derivative compound and use thereof
Kong Joo Lee, Seoul (KR); Hee-Yoon Lee, Daejeon (KR); Je Jin Lee, Seoul (KR); Hwang Suk Kim, Suwon-si (KR); Ji-Wan Seo, Daegu (KR); Hongsoo Lee, Daejeon (KR); Ji Soo Shin, Seoul (KR); and Bo-kyung Kim, Incheon (KR)
Assigned to EWHA University—Industry Collaboration Foundation, Seoul (KR)
Appl. No. 17/059,754
Filed by EWHA UNIVERSITY—INDUSTRY COLLABORATION FOUNDATION, Seoul (KR)
PCT Filed May 30, 2019, PCT No. PCT/KR2019/006519
§ 371(c)(1), (2) Date Nov. 30, 2020,
PCT Pub. No. WO2019/231262, PCT Pub. Date Dec. 5, 2019.
Claims priority of application No. 10-2018-0062122 (KR), filed on May 30, 2018.
Prior Publication US 2021/0214324 A1, Jul. 15, 2021
Int. Cl. C07D 303/18 (2006.01); A23L 33/10 (2016.01); A61P 35/04 (2006.01); C07C 35/21 (2006.01); C07C 43/23 (2006.01); C07C 235/56 (2006.01)
CPC C07D 303/18 (2013.01) [A23L 33/10 (2016.08); A61P 35/04 (2018.01); C07C 35/21 (2013.01); C07C 43/23 (2013.01); C07C 235/56 (2013.01)] 13 Claims
 
1. A biphenyl derivative compound of the following Formula 1 or a pharmaceutically acceptable salt thereof:

OG Complex Work Unit Chemistry
wherein
L is —(CH2—CH2)—, and
each of R1, R2, R3 and R4 is independently hydroxy or methoxy.