US 11,938,295 B2
Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
Jeffrey A. Shimizu, Poway, CA (US); Mitchell Lawrence Jones, La Jolla, CA (US); Mark Sasha Drlik, Victoria (CA); Iman Niknia, Victoria (CA); Nathan John Muller, Victoria (CA); Tuyen Nguyen, Victoria (CA); Christopher Loren Wahl, San Diego, CA (US); Edward Mudge, Cambridgeshire (GB); Nicholas Mark Salt, Cambridgeshire (GB); Nia Eleri Stevens, Cambridgeshire (GB); Stuart Robert Abercrombie, Cambridgeshire (GB); Christopher Ian Bunce, Cambridgeshire (GB); Ryan Elliott Jones, Turks and Caicos Island (CA); Kevin Howe, London (GB); Pejman Rahimian, Colleyville, TX (US); and Nelson Quintana, Temecula, CA (US)
Assigned to Biora Therapeutics, Inc., San Diego, CA (US)
Filed by Biora Therapeutics, Inc., San Diego, CA (US)
Filed on Sep. 15, 2022, as Appl. No. 17/945,890.
Application 17/945,890 is a continuation of application No. 17/784,453, granted, now 11,707,610, previously published as PCT/US2020/064590, filed on Dec. 11, 2020.
Claims priority of provisional application 63/086,630, filed on Oct. 2, 2020.
Claims priority of provisional application 63/027,427, filed on May 20, 2020.
Claims priority of provisional application 62/948,082, filed on Dec. 13, 2019.
Prior Publication US 2023/0017603 A1, Jan. 19, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61J 3/07 (2006.01); A61K 9/48 (2006.01); A61M 31/00 (2006.01); A61M 37/00 (2006.01)
CPC A61M 31/002 (2013.01) [A61K 9/4808 (2013.01); A61M 37/0015 (2013.01); A61M 2037/0061 (2013.01); A61M 2210/1042 (2013.01)] 20 Claims
 
1. An ingestible device, comprising:
a volume of liquid in a housing;
at least one nozzle extending through the housing, the nozzle having an opening of 0.1 to 0.5 mm;
a drive force generator in the housing for exerting a drive force on a piston in the housing, the piston between the drive force generator and the nozzle;
the drive force generator, when actuated, exerting a drive force on the piston resulting in:
a peak fluid pressure of about 100 psig to about 2056 psig; and
a peak jet power of about 1 to about 6.6 Watts.