	US 11,938,103 B2
	Potentiation of helminth treatment
Sarah George, Oakdale (AU); Peter Rolfe, Gunning (AU); and Chouaib Tahtaoui, Rixheim (FR)
Assigned to Elanco Tiergesundheit AG, Greenfield, IN (US)
Appl. No. 17/281,914
Filed by Elanco Tiergesundheit AG, Greenfield, IN (US)
PCT Filed Sep. 30, 2019, PCT No. PCT/US2019/053750 § 371(c)(1), (2) Date Mar. 31, 2021, PCT Pub. No. WO2020/072343, PCT Pub. Date Apr. 9, 2020.
Claims priority of provisional application 62/741,120, filed on Oct. 4, 2018.
Prior Publication US 2022/0008366 A1, Jan. 13, 2022
Int. Cl. A61K 31/167 (2006.01); A61K 31/63 (2006.01); A61P 33/10 (2006.01)

CPC A61K 31/167 (2013.01) [A61K 31/63 (2013.01); A61P 33/10 (2018.01)]

8 Claims

1. A method of treating liver fluke infections in a mammal in need of such treatment comprising administering an effective amount of diamphenethide in combination with an effective amount of clorsulon,

wherein the effective amount of diamphenethide is 20-80 mg/kg; and

wherein the effective amount of clorsulon is 3-10 mg/kg.