US 12,262,125 B2
Systems, methods and computer programs for a microscope system and for determining a transformation function
George Themelis, Lindau (DE); and Tobias Wilken, Binningen (CH)
Assigned to Leica Instruments (Singapore) Pte Ltd., Singapore (SG)
Appl. No. 17/995,116
Filed by LEICA INSTRUMENTS (SINGAPORE) PTE. LTD., Singapore (SG)
PCT Filed Mar. 8, 2021, PCT No. PCT/EP2021/055724
§ 371(c)(1), (2) Date Sep. 30, 2022,
PCT Pub. No. WO2021/197763, PCT Pub. Date Oct. 7, 2021.
Claims priority of application No. 20167604 (EP), filed on Apr. 1, 2020.
Prior Publication US 2023/0217120 A1, Jul. 6, 2023
Int. Cl. H04N 23/85 (2023.01); G06T 7/90 (2017.01); H04N 5/265 (2006.01); H04N 23/13 (2023.01); H04N 23/45 (2023.01)
CPC H04N 23/85 (2023.01) [G06T 7/90 (2017.01); H04N 5/265 (2013.01); H04N 23/13 (2023.01); H04N 23/45 (2023.01); G06T 2207/10024 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/20212 (2013.01); G06T 2207/30004 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A system for a microscope system, the system comprising one or more processors and one or more storage devices, wherein the system is configured to:
obtain first imaging sensor data from a first imaging sensor of a microscope of the microscope system and second imaging sensor data from a second imaging sensor of the microscope, the first imaging sensor data comprising sensor data on light sensed in a first plurality of mutually separated wavelength bands, the second imaging sensor data comprising sensor data on light sensed in a second plurality of mutually separated wavelength bands, wherein the wavelength bands of the first plurality of mutually separated wavelength bands or of the second plurality of mutually separated wavelength bands are wavelength bands that are used for fluorescence imaging,
wherein the system is configured to use the first and the second imaging sensor to perform reflectance imaging; and
generate a composite color image based on the first imaging sensor data and based on the second imaging sensor data, the composite color image being based on a plurality of color channels,
wherein the composite color image is generated using a transformation function to define a transformation to be performed between the imaging sensor data and the composite color image, such that the composite color image is generated using sensor data on light sensed in each wavelength band of the first and second plurality of mutually separated wavelength bands.