US 12,259,384 B2
Membrane and droplet-interface bilayer systems and methods
Matthew A. Holden, Amherst, MA (US); Max J. Lein, Belmont, MA (US); Arash Manafirad, Amherst, MA (US); and Dan Ezra Aurian-Blajeni, Newport, RI (US)
Assigned to UNIVERSITY OF MASSACHUSETTS, Boston, MA (US)
Filed by University of Massachusetts, Boston, MA (US)
Filed on May 1, 2023, as Appl. No. 18/309,941.
Application 18/309,941 is a continuation of application No. 17/724,894, filed on Apr. 20, 2022, granted, now 11,674,955.
Application 17/724,894 is a continuation of application No. 16/838,102, filed on Apr. 2, 2020, granted, now 11,340,220, issued on May 24, 2022.
Application 16/838,102 is a continuation of application No. 15/741,103, granted, now 10,641,764, issued on May 5, 2020, previously published as PCT/US2016/040665, filed on Jul. 1, 2016.
Claims priority of provisional application 62/187,951, filed on Jul. 2, 2015.
Prior Publication US 2024/0027437 A1, Jan. 25, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/543 (2006.01); B01J 13/08 (2006.01); G01N 33/68 (2006.01)
CPC G01N 33/5432 (2013.01) [B01J 13/08 (2013.01); G01N 33/6872 (2013.01); G01N 2500/20 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A system comprising a membrane separating first and second volumes of aqueous solution, the membrane comprising a lipid bilayer and an ion channel providing a passageway from one side of the membrane to the other, wherein the membrane contains 30% or less by weight of an amphiphilic polymer, and wherein the first and/or second aqueous solutions comprise a transcription/translation extract.