US 12,259,322 B2
Detection method and detection system using suspension liquid biochip
Jianqiu Fang, Hangzhou (CN); Wanwan Li, Shanghai (CN); and Chunmei Zhong, Hangzhou (CN)
Appl. No. 17/605,842
Filed by HANGZHOU SHINEDO BIOTECH CO., LTD., Hangzhou (CN)
PCT Filed Apr. 22, 2020, PCT No. PCT/CN2020/086225
§ 371(c)(1), (2) Date Jun. 3, 2022,
PCT Pub. No. WO2020/216261, PCT Pub. Date Oct. 29, 2020.
Claims priority of application No. 201910329309.8 (CN), filed on Apr. 23, 2019; and application No. 201910329326.1 (CN), filed on Apr. 23, 2019.
Prior Publication US 2022/0299441 A1, Sep. 22, 2022
Int. Cl. G01N 21/64 (2006.01)
CPC G01N 21/6428 (2013.01) [G01N 21/6452 (2013.01); G01N 2021/6421 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A detection system using a suspension liquid biochip, comprising:
a detection and analysis component, and a housing;
wherein the housing comprises an upper cover, a bottom plate and four side walls, and a cavity is formed inside the housing,
wherein a first recess is provided at one corner of four corners formed by the four side walls and the bottom plate, a mounting hole is provided in the first recess for installation of a rotatable clamp;
the clamp is configured to clamp a tube, and the clamp is provided with a first clamping hole, a second clamping hole, a third clamping hole and a fourth clamping hole; the first clamping hole is positioned opposite to the third clamping hole, and the second clamping hole is positioned opposite to the fourth clamping hole;
the first clamping hole and the third clamping hole are configured for an insertion of a first tube, and the second clamping hole and the fourth clamping hole are configured for an insertion of a second tube; an axis of the first clamping hole and the third clamping hole is perpendicular to an axis of the second clamping hole and the fourth clamping hole;
wherein the clamp includes a base and a plurality of clamping jaws, and the plurality of clamping jaws are arranged in two horizontal rows and arranged in two vertical columns on the base; two horizontal rows are arranged at intervals, and the first clamping hole and the third clamping hole are located between two horizontal rows; two vertical columns are arranged at intervals, and the second clamping hole and the fourth clamping hole are arranged between two vertical columns;
the base comprises a rotatable connecting post, which is installed in the mounting hole; the plurality of clamping jaws are connected with the connecting post, and the connecting post is configured to be rotatable in vertical directions to drive the plurality of clamping jaws to rotate in vertical directions, thereby the clamp is rotatable in vertical directions to make an opening of the first tube or an opening of the second tube face a direction suitable for use during the clamping of the first tube or the second tube,
wherein a plurality of catch grooves are provided on a surface of the connecting post; the plurality of catch grooves are distributed along a circumferential direction,
wherein the base further comprises a movable restricting member, and the restricting member includes an end, the restricting member is configured to be movable to make the end be inserted into the catch groove and be withdrawn from the catch groove; when the end of the restricting member is inserted into the catch groove, a rotation of the connecting post is restricted; after the end of the restricting member withdraws from the catch groove, a restriction on the connecting post is released, and
the connecting post is configured to be rotatable against the restricting member to make the restricting member move and make the end of the restricting member withdraw from the catch groove, and the end of the restricting member is configured to be inserted into a next catch groove when the next catch groove is rotated to be opposite to the end of the restricting member.