US 12,258,612 B2
Random heteropolymers preserve protein function in foreign environments
Ting Xu, Berkeley, CA (US); Brian Panganiban, Berkeley, CA (US); and Tao Jiang, Berkeley, CA (US)
Assigned to The Regents of the University of California, Oakland, CA (US)
Filed by The Regents of the University of California, Oakland, CA (US)
Filed on Mar. 4, 2023, as Appl. No. 18/178,505.
Application 18/178,505 is a division of application No. 16/907,284, filed on Jun. 21, 2020, granted, now 11,629,372.
Application 16/907,284 is a continuation of application No. PCT/US2019/013546, filed on Jan. 14, 2019.
Claims priority of provisional application 62/618,537, filed on Jan. 17, 2018.
Prior Publication US 2023/0220442 A1, Jul. 13, 2023
Int. Cl. C12Q 1/34 (2006.01); C08L 89/00 (2006.01); C12N 9/16 (2006.01); G01N 33/68 (2006.01)
CPC C12Q 1/34 (2013.01) [C08L 89/00 (2013.01); C12N 9/16 (2013.01); C12Y 301/08001 (2013.01); G01N 33/68 (2013.01); C08L 2203/02 (2013.01)] 20 Claims
 
1. A composition for preserving protein function in foreign environments, the composition comprising a complex of an active protein and statistically random heteropolymers (SRHPs) in an organic solvent, wherein the SRHPs comprising monomers: methyl methacrylate (MMA), oligo (ethylene glycol) methacrylate (OEGMA), 3-sulfopropyl methacrylate potassium salt (3-SPMA) and 2-ethylhexyl methacrylate (2-EHMA).