US 12,258,582 B2
Method of blood pooling and storage
Beth Shaz, New York, NY (US); and Christopher D. Hillyer, New York, NY (US)
Assigned to New York Blood Center, Inc., New York, NY (US)
Filed by New York Blood Center, Inc., New York, NY (US)
Filed on Jul. 17, 2019, as Appl. No. 16/514,689.
Application 16/514,689 is a continuation of application No. 13/483,379, filed on May 30, 2012, granted, now 10,385,317, issued on Aug. 20, 2019.
Application 13/483,379 is a continuation in part of application No. PCT/US2011/062460, filed on Nov. 29, 2011.
Application 13/483,379 is a continuation in part of application No. 13/306,759, filed on Nov. 29, 2011, granted, now 8,512,942, issued on Aug. 20, 2013.
Claims priority of provisional application 61/649,121, filed on May 18, 2012.
Claims priority of provisional application 61/417,770, filed on Nov. 29, 2010.
Prior Publication US 2019/0338248 A1, Nov. 7, 2019
Int. Cl. G01N 33/80 (2006.01); A01K 5/01 (2006.01); A01K 5/02 (2006.01); A01N 1/02 (2006.01); A61K 35/14 (2015.01); A61K 35/16 (2015.01); A61K 35/18 (2015.01); A61K 35/19 (2015.01); A61M 1/02 (2006.01); A61M 1/34 (2006.01); C12N 5/078 (2010.01)
CPC C12N 5/0641 (2013.01) [A01K 5/0114 (2013.01); A01K 5/02 (2013.01); A01K 5/0291 (2013.01); A01N 1/02 (2013.01); A01N 1/021 (2013.01); A01N 1/0226 (2013.01); A61K 35/14 (2013.01); A61K 35/16 (2013.01); A61K 35/18 (2013.01); A61K 35/19 (2013.01); A61M 1/0272 (2013.01); A61M 1/342 (2013.01); A61M 1/3496 (2013.01); C12N 5/0644 (2013.01); A61M 2202/0429 (2013.01); A61M 2202/20 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A method for preparing uniform dose blood component transfusion products from a plurality of whole blood units of a same blood group and type comprising:
a) pooling a plurality of units of whole blood from different donors of the same blood group and type;
b) leukoreducing the pooled whole blood;
c) treating the pooled whole blood to inactivate one or more pathogens;
wherein the leukoreduction and inactivation steps are performed in either order;
d) separating at least one of an RBC component, a platelet component, and a plasma component from the leukoreduced, pathogen-inactivated pooled whole blood;
and performing at least one of steps e), f), or g):
e) adding a storage solution to the RBC component and dividing the RBC component into uniform volume and dose RBC transfusion product units;
f) adding a storage solution to the platelet component and dividing the platelet component into uniform volume and dose platelet transfusion product units; and
g) dividing the plasma component into uniform volume and dose plasma transfusion product units.