	US 12,258,537 B2
	Composition containing highly unsaturated fatty acid or alkyl ester thereof and a method for producing the same
Nobushige Doisaki, Tsukuba (JP); Kiyomi Furihata, Hachioji (JP); and Hideaki Yamaguchi, Hachioji (JP)
Assigned to Nissui Corporation, Tokyo (JP)
Filed by Nissui Corporation, Tokyo (JP)
Filed on Dec. 26, 2023, as Appl. No. 18/396,499.
Application 18/396,499 is a continuation of application No. 17/962,984, filed on Oct. 10, 2022, granted, now 11,898,120.
Application 17/962,984 is a continuation of application No. 17/154,646, filed on Jan. 21, 2021, granted, now 11,499,119.
Application 17/154,646 is a continuation of application No. 16/881,352, filed on May 22, 2020, granted, now 11,248,190.
Application 16/881,352 is a continuation of application No. 16/404,662, filed on May 6, 2019, granted, now 10,696,924.
Claims priority of application No. 2018-232498 (JP), filed on Dec. 12, 2018.
Prior Publication US 2024/0166969 A1, May 23, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C11C 3/10 (2006.01); B01D 3/12 (2006.01); B01D 3/14 (2006.01); C11B 1/06 (2006.01); C11B 3/12 (2006.01); C11C 3/00 (2006.01)

CPC C11C 3/10 (2013.01) [C11B 1/06 (2013.01); C11B 3/12 (2013.01); C11C 3/003 (2013.01); B01D 3/12 (2013.01); B01D 3/143 (2013.01)]

7 Claims

1. A method for producing a composition containing a highly unsaturated fatty acid or an alkyl ester thereof, which comprises:

(1) at least one step selected from (a)-(c):

(a) reducing a monoacyl glycerol concentration in a composition containing a highly unsaturated fatty acid alkyl ester to less than 10,000 ppm, wherein the monoacyl glycerol comprises as constituent fatty acid a fatty acid that has 5 or more carbon atoms fewer than the highly unsaturated fatty acid that constitutes the highly unsaturated fatty acid alkyl ester to be enriched in the composition,

(b) reducing an iron concentration in a composition containing a highly unsaturated fatty acid alkyl ester to less than 0.20 ppm, and

(c) reducing a chlorine concentration in a composition containing a highly unsaturated fatty acid alkyl ester to less than 10 ppm;

(2) distilling the composition resulting from step (1) and collecting the main distillate fraction, thereby obtaining a composition comprising 50% by weight or more of fatty acid or fatty acid alkyl esters, wherein the concentration of 3-MCPD as found upon analyzing the main distillate fraction by American Oil Chemists' Society official method Cd 29b-13 assay A is less than 1.80 ppm.