	US 12,258,424 B2
	Polypeptides and compositions comprising the same
Kun Cheng, Overland Park, KS (US); Hao Liu, Rockville, MD (US); John Fetse, Mission, KS (US); and Umar-Farouk Mamani, Mission, KS (US)
Filed by Kun Cheng, Kansas City, MO (US); Hao Liu, Kansas City, MO (US); John Fetse, Kansas City, MO (US); and Umar-Farouk Mamani, Kansas City, MO (US)
Filed on Oct. 21, 2021, as Appl. No. 17/507,301.
Claims priority of provisional application 63/104,256, filed on Oct. 22, 2020.
Claims priority of provisional application 63/094,653, filed on Oct. 21, 2020.
Prior Publication US 2022/0119451 A1, Apr. 21, 2022
Int. Cl. C07K 7/08 (2006.01); A61K 38/00 (2006.01); C07K 7/06 (2006.01)

CPC C07K 7/08 (2013.01) [C07K 7/06 (2013.01); A61K 38/00 (2013.01)]

16 Claims

1. A composition, comprising:

a therapeutic agent, the therapeutic agent comprising a polypeptide that comprises one or more amino acid sequences selected from the group consisting of:

SEQ ID NO: 2;

SEQ ID NO:5, wherein a disulfide bond is present between the cysteine amino acids at positions 1 and 12 of SEQ ID NO:5; and

SEQ ID NO:7.