	US 12,258,396 B1
	Methods of using immunotherapeutics that bind folate receptor alpha
Seah Lim, Wilmington, DE (US)
Assigned to MEDICOVESTOR, INC., Wilmington, DE (US)
Filed by Medicovestor, Inc., Wilmington, DE (US)
Filed on Feb. 2, 2024, as Appl. No. 18/431,767.
Int. Cl. C07K 16/28 (2006.01); G01N 33/574 (2006.01)

CPC C07K 16/28 (2013.01) [G01N 33/574 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); G01N 2333/705 (2013.01)]

9 Claims

1. A method of treating cancer in a human subject, comprising:

administering an immunotherapeutic agent to the human subject, wherein the immunotherapeutic agent comprises an antibody that binds human folate receptor alpha, wherein said antibody comprises:

a first variable domain that further comprises a VH CDR1 region comprising SEQ ID NO: 5, a VH CDR2 region comprising SEQ ID NO: 6, and a VH CDR3 region comprising SEQ ID NO: 7; and

a second variable domain that further comprises a VL CDR1 region comprising SEQ ID NO: 8, a VL CDR2 region comprising SEQ ID NO: 9, and a VL CDR3 region comprising SEQ ID NO: 10.