US 12,258,355 B2
Probes for imaging huntingtin protein
Celia Dominguez, Los Angeles, CA (US); Samuel Coe, Northampton (GB); Peter David Johnson, Oxfordshire (GB); Michael Edward Prime, Abingdon (GB); Christopher John Brown, Abingdon (GB); Sébastien René Gabriel Galan, Abingdon (GB); Paul Richard Giles, Abingdon (GB); Jonathan Bard, New York, NY (US); Elise Lucienne Paulette Gadouleau, Didcot (GB); Thomas Martin Krülle, Oxford (GB); Daniel Clark-Frew, Wantage (GB); John Wityak, Carlsbad, CA (US); Alex Kiselyov, New York, NY (US); and Sarah Hayes, Oxfordshire (GB)
Assigned to CHDI Foundation, Inc., New York, NY (US)
Filed by CHDI Foundation, Inc., New York, NY (US)
Filed on Aug. 5, 2022, as Appl. No. 17/881,895.
Application 17/881,895 is a continuation of application No. 17/558,397, filed on Dec. 21, 2021, abandoned.
Application 17/558,397 is a continuation of application No. 17/325,038, filed on May 19, 2021, abandoned.
Application 17/325,038 is a continuation of application No. 16/530,594, filed on Aug. 2, 2019, granted, now 11,059,836.
Application 16/530,594 is a continuation of application No. 15/507,208, granted, now 10,479,802, previously published as PCT/US2015/047407, filed on Aug. 28, 2015.
Claims priority of provisional application 62/043,603, filed on Aug. 29, 2014.
Prior Publication US 2023/0212190 A1, Jul. 6, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 513/04 (2006.01); A61B 5/00 (2006.01); A61B 6/03 (2006.01); A61K 51/04 (2006.01); C07D 263/57 (2006.01); C07D 405/14 (2006.01); C07D 413/04 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01)
CPC C07D 513/04 (2013.01) [A61B 5/0035 (2013.01); A61B 6/032 (2013.01); A61B 6/037 (2013.01); A61K 51/0455 (2013.01); A61K 51/0459 (2013.01); A61K 51/0463 (2013.01); C07D 263/57 (2013.01); C07D 405/14 (2013.01); C07D 413/04 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01)] 14 Claims
 
1. A compound which is:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.