US 12,258,320 B2
Solid state forms of mavacamten and process for preparation thereof
Lorena Kordić, Rab (HR); and Dijana Škalec Šamec, Jastrebarsko (HR)
Assigned to ASSIA CHEMICAL INDUSTRIES LTD., Tel Aviv (IL)
Filed by Assia Chemical Industries Ltd., Tel Aviv (IL)
Filed on Mar. 20, 2024, as Appl. No. 18/610,777.
Application 18/610,777 is a continuation of application No. 17/792,754, previously published as PCT/US2021/015358, filed on Jan. 28, 2021.
Claims priority of provisional application 63/008,009, filed on Apr. 10, 2020.
Claims priority of provisional application 62/980,503, filed on Feb. 24, 2020.
Claims priority of provisional application 62/966,665, filed on Jan. 28, 2020.
Prior Publication US 2024/0228442 A1, Jul. 11, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 239/10 (2006.01)
CPC C07D 239/10 (2013.01) [C07B 2200/13 (2013.01)] 24 Claims
 
1. A crystalline form of Mavacamten designated as Form 1, characterized by an X-ray powder diffraction pattern substantially as depicted in FIG. 1, wherein the peak at 28.48 belongs to silicon.