	US 12,257,586 B2
	Porous particle composite for PCR with heat dissipation function
Sang Kyung Kim, Seoul (KR); Bong Kyun Kim, Seoul (KR); Jung Min Kim, Seoul (KR); and Seungwon Jung, Seoul (KR)
Assigned to Korea Institute of Science and Technology, Seoul (KR)
Appl. No. 17/055,167
Filed by KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, Seoul (KR)
PCT Filed May 14, 2019, PCT No. PCT/KR2019/005796 § 371(c)(1), (2) Date Nov. 13, 2020, PCT Pub. No. WO2019/221489, PCT Pub. Date Nov. 21, 2019.
Claims priority of application No. 10-2018-0055629 (KR), filed on May 15, 2018.
Prior Publication US 2021/0197201 A1, Jul. 1, 2021
Int. Cl. C12Q 1/68 (2018.01); B01L 7/00 (2006.01); C09K 5/14 (2006.01); C12Q 1/686 (2018.01)

CPC B01L 7/00 (2013.01) [C09K 5/14 (2013.01); C12Q 1/686 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/1861 (2013.01)]

13 Claims

1. A porous particle composite for PCR, comprising porous particles and photothermal nanoelements;

wherein the porous particles are a hydrophilic polymer in solid state,

wherein a porosity of the porous particles is 10-95 v/v % and a particle diameter of the porous particles is 10 μm to 1 mm;

wherein the photothermal nanoelements have a diameter or length of 1-500 nm and are fixed to the porous particles;

wherein when exposed to light having a wavelength of 800 nm the photothermal nanoelements absorb the light and generate heat; and

wherein the photothermal nanoelements are not rod-shaped.