US 12,257,459 B2
System and method for open-loop ultrasound therapy
Mathieu Allard, Mississauga (CA)
Assigned to Profound Medical Inc., Mississauga (CA)
Filed by Profound Medical Inc., Mississauga (CA)
Filed on Dec. 28, 2023, as Appl. No. 18/398,565.
Application 18/398,565 is a division of application No. 16/984,367, filed on Aug. 4, 2020, granted, now 11,944,847.
Claims priority of provisional application 62/882,662, filed on Aug. 5, 2019.
Prior Publication US 2024/0123264 A1, Apr. 18, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61N 7/00 (2006.01)
CPC A61N 7/00 (2013.01) [A61N 2007/0004 (2013.01); A61N 2007/0043 (2013.01); A61N 2007/0052 (2013.01); A61N 2007/0078 (2013.01); A61N 2007/0086 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A system for open-loop ultrasound therapy delivery, comprising:
a therapeutic ultrasound applicator having a distal tip that includes an ultrasound transducer;
an ultrasound imaging probe that acquires ultrasound images of the patient's urethra and prostate;
an ultrasound applicator positioning system mechanically coupled to the therapeutic ultrasound applicator;
a microprocessor-based UA positioning system controller in electrical communication with the ultrasound applicator positioning system, the UA positioning system controller configured to adjust a position and orientation of the ultrasound transducer to deliver therapeutic ultrasound energy to the patient's prostate according to a treatment plan; and
a microprocessor-based computer in electrical communication with the therapeutic ultrasound applicator, the ultrasound imaging probe, and the UA positioning system controller, the computer having a non-volatile memory that stores computer-readable instructions that, when executed by the microprocessor, cause the computer to:
receive one or more inputs corresponding to the treatment plan, the treatment plan including a predetermined limited angular range for the therapeutic ultrasound energy that avoids the patient's rectum, neurovascular bundles, and internal organs other than the patient's prostate, and
generate control signals that cause the UA positioning system controller to rotate the ultrasound transducer over the predetermined limited angular range and to simultaneously deliver therapeutic ultrasound energy from the ultrasound transducer over the predetermined limited angular range,
wherein the therapeutic ultrasound is delivered without temperature feedback data.