US 12,257,456 B2
Systems and methods for dynamic control of radiation dose in radiation therapy
Ke Sheng, Los Angeles, CA (US); and Qihui Lyu, Oakland, CA (US)
Assigned to The Regents of the University of California, Oakland, CA (US)
Appl. No. 17/779,899
Filed by The Regents of the University of California, Oakland, CA (US)
PCT Filed Nov. 25, 2020, PCT No. PCT/US2020/062392
§ 371(c)(1), (2) Date May 25, 2022,
PCT Pub. No. WO2021/108684, PCT Pub. Date Jun. 3, 2021.
Claims priority of provisional application 62/940,055, filed on Nov. 25, 2019.
Prior Publication US 2023/0015121 A1, Jan. 19, 2023
Int. Cl. A61N 5/10 (2006.01)
CPC A61N 5/1067 (2013.01) [A61N 5/1036 (2013.01); A61N 5/1045 (2013.01); A61N 5/1081 (2013.01); A61N 2005/1087 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A radiation therapy system comprising:
a radiation source configured to emit a radiation therapy beam toward a patient having a tumor to effectuate a radiation therapy process;
a plurality of dynamically-adjustable collimators, each of the dynamically-adjustable collimators configured to be independently controlled to create a respective attenuation profile at each of the dynamically-adjustable collimators; and
a controller device configured to:
adjust the respective attenuation profile at each of the dynamically-adjustable collimators based on a shape of the tumor relative to a respective beam path defined by a path followed from the radiation source through a respective dynamically-adjustable collimator and to the tumor of the patient; and
effectuate the radiation therapy process by controlling at least one of a position of the radiation source or the plurality of dynamically-adjustable collimators relative to the patient to deliver the radiation therapy beam through each of the plurality of dynamically-adjustable collimators to match a shape of the radiation therapy beam to the shape of the tumor relative to the respective beam path defined by the path followed from the radiation source through a respective dynamically-adjustable collimator and to the tumor of the patient.