US 12,257,435 B2
Assessment and adjustment of time-varying pulse patterns in a spinal cord stimulator system
Rosana Esteller, Santa Clarita, CA (US); Jessica Block, Los Angeles, CA (US); and Changfang Zhu, Valencia, CA (US)
Assigned to Boston Scientific Neuromodulation Corporation, Valencia, CA (US)
Appl. No. 17/753,866
Filed by Boston Scientific Neuromodulation Corporation, Valencia, CA (US)
PCT Filed Sep. 24, 2020, PCT No. PCT/US2020/052520
§ 371(c)(1), (2) Date Mar. 16, 2022,
PCT Pub. No. WO2021/080727, PCT Pub. Date Apr. 29, 2021.
Claims priority of provisional application 62/923,818, filed on Oct. 21, 2019.
Prior Publication US 2022/0347479 A1, Nov. 3, 2022
Int. Cl. A61N 1/36 (2006.01); A61N 1/05 (2006.01); A61N 1/372 (2006.01)
CPC A61N 1/36071 (2013.01) [A61N 1/0551 (2013.01); A61N 1/36132 (2013.01); A61N 1/36178 (2013.01); A61N 1/36189 (2013.01); A61N 1/37247 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A method for determining stimulation for a patient having an implantable stimulator device, comprising:
(a) applying different modulation functions to time-invariant pulse parameters to create a plurality of different time-varying pulse waveforms, wherein each of the modulation functions modulates at least one of the time-invariant pulse parameters;
(b) applying each of the time-varying pulse waveforms to the patient via the implantable stimulator device;
(c) obtaining at least one measurement of a neural response evoked by recruitment of neural fibers in the patient's tissue in response to each of the applied time-varying pulse waveforms; and
(d) selecting one or more of the time-varying pulse waveforms for the patient based at least in part on the at least one measurements.