US 12,257,375 B2
Apparatus for extracorporeal treatment of blood
Dominique Pouchoulin, Tramoyes (FR)
Assigned to Gambro Lundia AB, Lund (SE)
Filed by GAMBRO LUNDIA AB, Lund (SE)
Filed on Mar. 7, 2019, as Appl. No. 16/295,878.
Application 16/295,878 is a continuation of application No. 15/240,231, filed on Aug. 18, 2016, granted, now 10,258,726.
Application 15/240,231 is a continuation of application No. 14/388,295, abandoned, previously published as PCT/IB2013/052275, filed on Mar. 22, 2013.
Claims priority of provisional application 61/616,519, filed on Mar. 28, 2012.
Claims priority of application No. 12002252 (EP), filed on Mar. 28, 2012.
Prior Publication US 2019/0201605 A1, Jul. 4, 2019
Int. Cl. A61M 1/16 (2006.01); A61M 1/34 (2006.01); A61M 1/36 (2006.01)
CPC A61M 1/1647 (2014.02) [A61M 1/16 (2013.01); A61M 1/1605 (2014.02); A61M 1/1643 (2014.02); A61M 1/34 (2013.01); A61M 1/3403 (2014.02); A61M 1/341 (2014.02); A61M 1/3413 (2013.01); A61M 1/3434 (2014.02); A61M 1/3441 (2013.01); A61M 1/3451 (2014.02); A61M 1/361 (2014.02); A61M 1/3638 (2014.02); A61M 2205/18 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/3393 (2013.01); A61M 2205/502 (2013.01); A61M 2205/505 (2013.01); A61M 2205/52 (2013.01)] 9 Claims
OG exemplary drawing
 
1. An apparatus for extracorporeal treatment of blood comprising:
a filtration unit having a primary chamber and a secondary chamber separated by a semi-permeable membrane;
a blood withdrawal line connected to an inlet of the primary chamber, and a blood return line connected to an outlet of the primary chamber said blood lines being designed to be connected to a patient cardiovascular system;
a blood pump for controlling the flow of blood through the blood lines;
an effluent fluid line connected to an outlet of the secondary chamber;
an ultrafiltration actuator connected to the effluent fluid line and configured to cause a transfer of fluid from the primary to the secondary chamber; and
a control unit configured to control the ultrafiltration actuator based on a set value for patient fluid removal rate, said set value being a setting imposed on the ultrafiltration actuator defining a rate of fluid removal from a patient, wherein the control unit is further configured to determine when the ultrafiltration actuator is operated or when the ultrafiltration actuator is not operated, and wherein the control unit is further configured to execute at two or more check points during patient treatment a control procedure comprising:
calculating an updated set value for said patient fluid removal rate as a function of said set value for the patient fluid removal rate and of check information for a selected check point of the two or more check points, wherein said check information is selected from the group of:
an effective time portion of a time period preceding the selected check point during which said ultrafiltration actuator is operated, wherein the effective time portion is calculated by reducing the duration of the time period between a preceding check point and the selected check point by down time during the time period during which said ultrafiltration actuator is not operated, and
a down time portion of a time period preceding the selected check point during which said ultrafiltration actuator is not operated.