US 12,257,310 B2
Reactive and sorbent materials
Dominic P. Dinovo, Dublin, OH (US); Andrew Dinovo, Columbus, OH (US); Matthew F. Smiechowski, Westerville, OH (US); and Francis H. Verhoff, Cincinnati, OH (US)
Filed by Dominic P. Dinovo, Dublin, OH (US); Andrew Dinovo, Columbus, OH (US); Matthew F. Smiechowski, Westerville, OH (US); and Francis H. Verhoff, Cincinnati, OH (US)
Filed on Oct. 20, 2017, as Appl. No. 15/789,941.
Claims priority of provisional application 62/410,477, filed on Oct. 20, 2016.
Prior Publication US 2018/0110868 A1, Apr. 26, 2018
Int. Cl. A61K 47/61 (2017.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 35/74 (2015.01); A61K 36/062 (2006.01); A61K 38/47 (2006.01); A61K 47/69 (2017.01); C12N 11/02 (2006.01); C12N 11/06 (2006.01); C12N 11/10 (2006.01); C12N 11/14 (2006.01)
CPC A61K 47/61 (2017.08) [A61K 9/0053 (2013.01); A61K 9/146 (2013.01); A61K 35/74 (2013.01); A61K 36/062 (2013.01); A61K 38/47 (2013.01); A61K 47/6921 (2017.08); C12N 11/02 (2013.01); C12N 11/06 (2013.01); C12N 11/10 (2013.01); C12N 11/14 (2013.01); C12Y 302/01017 (2013.01)] 19 Claims
 
1. A material comprising a non-encapsulated form of a biological component crosslinked and covalently bonded to a support matrix;
wherein the support matrix includes a polyamine and at least one support material;
wherein the biological component is an enzyme; and
wherein the material is more active than the biological component the material was formed from, on an equivalent basis.