US 12,257,303 B2
Methods and composition for induction of immune response
Paul Joseph Dominowski, Kalamazoo, MI (US); Duncan Mwangi, Portage, MI (US); Joseph M. Bricker, Parsippany, NJ (US); Dennis L. Foss, Mattawan, MI (US); Sharath K. Rai, Portage, MI (US); and Suman Mahan, Kalamazoo, MI (US)
Assigned to Zoetis Services LLC, Parsippany, NJ (US)
Filed by Zoetis Services LLC, Parsippany, NJ (US)
Filed on Apr. 28, 2022, as Appl. No. 17/731,348.
Application 17/731,348 is a continuation of application No. 15/039,733, granted, now 11,318,200, issued on May 3, 2022, previously published as PCT/US2014/066767, filed on Nov. 21, 2014.
Claims priority of provisional application 61/909,045, filed on Nov. 26, 2013.
Prior Publication US 2023/0100089 A1, Mar. 30, 2023
Int. Cl. A61K 39/39 (2006.01); A61K 31/14 (2006.01); A61K 31/575 (2006.01); A61K 31/7028 (2006.01); A61K 31/704 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01)
CPC A61K 39/39 (2013.01) [A61K 31/14 (2013.01); A61K 31/575 (2013.01); A61K 31/7028 (2013.01); A61K 31/704 (2013.01); A61K 45/06 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55572 (2013.01); A61K 2039/55577 (2013.01)] 19 Claims
 
1. A method of inducing an immune response to an infection caused by a virus in a mammal or bird, comprising administering a substantially antigen-free composition comprising a saponin, a sterol, a quaternary amine, and a polyacrylic polymer to the mammal or bird, wherein said virus is selected from the group consisting of avian herpesvirus, Bovine herpesviruses, Canine herpesviruses, Equine herpesviruses, Feline viral rhinotracheitis virus, Marek's disease virus, Ovine herpesviruses, Porcine herpesviruses, Pseudorabies virus.