US 12,257,302 B2
Universal vaccine platform
Hugh Mason, Phoenix, AZ (US); Andrew Diamos, Tempe, AZ (US); Mary Pardhe, Phoenix, AZ (US); and Brandon Favre, Los Gatos, CA (US)
Assigned to Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US)
Filed by Hugh Mason, Phoenix, AZ (US); Andrew Diamos, Tempe, AZ (US); Mary Pardhe, Phoenix, AZ (US); and Brandon Favre, Los Gatos, CA (US)
Filed on Nov. 8, 2023, as Appl. No. 18/504,962.
Application 18/504,962 is a continuation of application No. 17/367,296, filed on Jul. 2, 2021, granted, now 11,865,174.
Application 17/367,296 is a continuation of application No. 16/404,698, filed on May 6, 2019, granted, now 11,058,766, issued on Jul. 13, 2021.
Claims priority of provisional application 62/821,599, filed on Mar. 21, 2019.
Claims priority of provisional application 62/667,414, filed on May 4, 2018.
Prior Publication US 2024/0216502 A1, Jul. 4, 2024
Int. Cl. A61K 39/12 (2006.01); A61K 39/00 (2006.01); A61K 39/145 (2006.01); A61K 39/29 (2006.01); A61P 31/20 (2006.01); C12N 7/00 (2006.01)
CPC A61K 39/292 (2013.01) [A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61P 31/20 (2018.01); C12N 7/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/575 (2013.01); A61K 2039/6056 (2013.01); A61K 2039/70 (2013.01); C12N 2710/20023 (2013.01); C12N 2710/20034 (2013.01); C12N 2710/20071 (2013.01); C12N 2730/10123 (2013.01); C12N 2730/10134 (2013.01); C12N 2730/10171 (2013.01); C12N 2760/16123 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16171 (2013.01); C12N 2770/24134 (2013.01); C12N 2770/24171 (2013.01)] 17 Claims
 
1. A recombinant immune complex comprising: an immunoglobulin heavy chain; an immunoglobulin light chain; an epitope tag, wherein the immunoglobulin heavy chain binds the epitope tag; and a fragment of a virus protein, wherein the fragment of the virus protein is linked to the N-terminus of the immunoglobulin heavy chain, the epitope tag is linked to the C-terminus of the immunoglobulin heavy chain, and the epitope tag is from a different protein than the virus protein.