US 12,257,275 B2
Probiotics and fermentation metabolites for the prevention and treatment of disease conditions in animals
Steven K. Kazemi, Denver, CO (US); and Naseer Sangwan, Chicago, IL (US)
Assigned to PURE CULTURES, INC., Denver, CO (US)
Filed by PURE CULTURES 2020, INC., Denver, CO (US)
Filed on Aug. 25, 2020, as Appl. No. 17/001,938.
Application 17/001,938 is a continuation of application No. 16/220,416, filed on Dec. 14, 2018, granted, now 10,758,577.
Claims priority of provisional application 62/598,730, filed on Dec. 14, 2017.
Prior Publication US 2020/0390834 A1, Dec. 17, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 35/747 (2015.01); A23K 10/18 (2016.01); A23K 50/10 (2016.01); A23K 50/30 (2016.01); A23K 50/40 (2016.01); A23K 50/75 (2016.01); A23L 33/135 (2016.01); A61K 9/16 (2006.01); A61K 35/00 (2006.01); A61K 35/744 (2015.01); A61K 45/06 (2006.01); A61P 1/00 (2006.01); A61P 31/04 (2006.01); C12P 19/04 (2006.01)
CPC A61K 35/747 (2013.01) [A23K 10/18 (2016.05); A23K 50/10 (2016.05); A23K 50/30 (2016.05); A23K 50/40 (2016.05); A23K 50/75 (2016.05); A23L 33/135 (2016.08); A61K 9/16 (2013.01); A61K 35/744 (2013.01); A61K 45/06 (2013.01); A61P 1/00 (2018.01); A61P 31/04 (2018.01); C12P 19/04 (2013.01); A23V 2002/00 (2013.01); A23V 2400/113 (2023.08); A23V 2400/143 (2023.08); A23V 2400/169 (2023.08); A23V 2400/173 (2023.08); A23V 2400/413 (2023.08); A23V 2400/427 (2023.08); A61K 2035/115 (2013.01)] 17 Claims
 
1. A composition comprising at least two microbes selected from the group consisting of Lactobacillus reuteri PCR7, Pediococcus acidilactici PCLL01, Enterococcus faecium PCEF02, Pediococcus pentosaceus PCPP01, and Lactobacillus fermentum PCF01, a medium comprising molasses, and wherein the composition further comprises one or more fermentation metabolites produced by the at least two microbes grown in combination in the medium, wherein the one or more fermentation metabolites are produced by fermentation of the molasses in the medium.