CPC A61K 31/343 (2013.01) [A61K 31/4439 (2013.01); A61K 31/444 (2013.01); A61K 31/4545 (2013.01); A61K 31/5377 (2013.01); A61P 9/06 (2018.01)] | 24 Claims |
1. A method for cardioverting a patient having an extended episode of paroxysmal or persistent AFib and who is deemed suitable for cardioversion, said method comprising:
a) administering a single oral dose of budiodarone or a pharmaceutically acceptable salt thereof to said patient in an amount from about 900 mg to about 2,000 mg, wherein the amount is sufficient to provide for a peak budiodarone blood plasma concentration in said patient of at least about 50 ng/mL and maintain a budiodarone blood plasma concentration in said patient of at least about 13 ng/mL for at least 6 hours wherein said patient's AFib heart rhythm cardioverts to sinus rhythm; and
b) monitoring a heart rhythm of said patient, subsequent to said administering, until the budiodarone blood plasma concentration is measured to be below about 20 ng/mL.
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