US 12,257,152 B2
Implant comprising nonbiologic portion and biologic portion
Peter M. Bonutti, Manalapan, FL (US)
Assigned to P TECH, LLC, Manalapan, FL (US)
Filed by P Tech, LLC, Manalapan, FL (US)
Filed on Jul. 27, 2023, as Appl. No. 18/360,335.
Application 18/360,335 is a continuation of application No. 15/382,105, filed on Dec. 16, 2016, granted, now 11,737,878.
Claims priority of provisional application 62/268,308, filed on Dec. 16, 2015.
Prior Publication US 2024/0000573 A1, Jan. 4, 2024
Int. Cl. A61F 2/28 (2006.01); A61F 2/30 (2006.01); A61L 27/04 (2006.01); A61L 27/36 (2006.01); A61L 27/56 (2006.01)
CPC A61F 2/2846 (2013.01) [A61L 27/04 (2013.01); A61L 27/3612 (2013.01); A61L 27/56 (2013.01); A61F 2002/2835 (2013.01); A61F 2002/3092 (2013.01); A61F 2002/3093 (2013.01); A61L 2430/02 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An implant for being implanted in a subject, the implant comprising:
a non-biologic, three-dimensional (3D) printed shell configured to be implanted in a joint of the subject, the shell including a porous region having a porosity;
bone tissue ingrown by incubation into pores of the porous region of the shell to form a bone part of the implant; and
cartilage tissue grown by incubation on the bone part,
wherein the porous region includes i) a first porous region having a first porosity, and ii) a second porous region underlying the first porous region and having a second porosity less than the first porosity, wherein the bone tissue includes i) cortical bone tissue ingrown by incubation into pores of the first porous region of the shell to form a cortical bone portion of the bone part of the implant, and ii) cancellous bone tissue ingrown by incubation into pores of the second porous region of the shell to form a cancellous bone portion of the bone part of the implant.