US 12,257,071 B2
Controlled sympathectomy and micro-ablation systems and methods
Landy Toth, Doylestown, PA (US); and Robert Schwartz, Inver Grove Heights, MN (US)
Assigned to Autonomix Medical, Inc., Ivyland, PA (US)
Filed by Autonomix Medical, Inc., Excelsior, MN (US)
Filed on May 20, 2021, as Appl. No. 17/325,833.
Application 17/325,833 is a continuation of application No. 16/005,037, filed on Jun. 11, 2018, granted, now 11,013,459.
Application 16/005,037 is a continuation of application No. 15/486,850, filed on Apr. 13, 2017, granted, now 10,022,085, issued on Jul. 17, 2018.
Application 15/486,850 is a continuation of application No. 14/638,832, filed on Mar. 4, 2015, granted, now 9,649,064, issued on May 16, 2017.
Application 14/638,832 is a continuation in part of application No. 14/374,466, granted, now 10,470,684, issued on Nov. 12, 2019, previously published as PCT/US2013/023157, filed on Jan. 25, 2013.
Claims priority of provisional application 61/948,963, filed on Mar. 6, 2014.
Claims priority of provisional application 61/590,812, filed on Jan. 26, 2012.
Claims priority of provisional application 61/613,097, filed on Mar. 20, 2012.
Prior Publication US 2021/0267542 A1, Sep. 2, 2021
Int. Cl. A61B 5/00 (2006.01); A61B 5/01 (2006.01); A61B 5/02 (2006.01); A61B 5/0205 (2006.01); A61B 5/0215 (2006.01); A61B 5/145 (2006.01); A61B 5/24 (2021.01); A61B 5/389 (2021.01); A61B 7/02 (2006.01); A61B 10/02 (2006.01); A61B 10/04 (2006.01); A61B 17/32 (2006.01); A61B 18/00 (2006.01); A61B 18/02 (2006.01); A61B 18/14 (2006.01); A61B 18/18 (2006.01); A61N 5/10 (2006.01); A61N 7/00 (2006.01); A61N 7/02 (2006.01)
CPC A61B 5/4839 (2013.01) [A61B 5/02007 (2013.01); A61B 5/02055 (2013.01); A61B 5/14532 (2013.01); A61B 5/24 (2021.01); A61B 5/389 (2021.01); A61B 5/6853 (2013.01); A61B 7/023 (2013.01); A61B 10/02 (2013.01); A61B 10/04 (2013.01); A61B 18/02 (2013.01); A61B 18/1445 (2013.01); A61B 18/1492 (2013.01); A61N 7/022 (2013.01); A61B 5/01 (2013.01); A61B 5/0215 (2013.01); A61B 2017/320069 (2017.08); A61B 2018/0022 (2013.01); A61B 2018/00267 (2013.01); A61B 2018/00404 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00511 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00636 (2013.01); A61B 2018/00648 (2013.01); A61B 2018/00702 (2013.01); A61B 2018/00839 (2013.01); A61B 2018/1467 (2013.01); A61B 2018/1475 (2013.01); A61B 18/1815 (2013.01); A61B 2018/1861 (2013.01); A61N 5/1048 (2013.01); A61N 2007/0026 (2013.01); A61N 2007/003 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A system, comprising:
a tool comprising:
one or more microfingers having substantially elongate structures;
a plurality of sensing tips electrically and mechanically coupled to the one or more microfingers, the plurality of sensing tips configured to interface with a wall of a lumen coupled to an organ of a subject;
one or more sensors; and
a control unit;
wherein the control unit of the tool is configured:
to apply a first procedure to a first region in a vicinity of the lumen via delivery of at least one of energy and a chemical utilizing a first subset of the plurality of sensing tips; and
to apply a second procedure to a second region in the vicinity of the lumen via delivery of at least one of energy and a chemical utilizing a second subset of the plurality of sensing tips, wherein the first region is farther from the organ than the second region, wherein the second subset of the plurality of sensing tips is different than the first subset of the plurality of sensing tips;
to monitor one or more physiologic parameters of the subject at a third region utilizing at least one of the one or more sensors after application of the second procedure, the third region being farther from the organ than the first region; and
to convey an outcome of the first procedure to an operator, the outcome being determined based at least in part on the monitored one or more physiologic parameters;
wherein the one or more microfingers are configured such that the first subset of the plurality of sensing tips bias against the wall of the lumen in the first region while the second subset of the plurality of sensing tips bias against the wall of the lumen in the second region during a single placement of the tool.