US 12,257,067 B2
Systems and methods for designation of REM and WAKE states
Hugi Hilmisson, Denver, CO (US)
Assigned to MYCARDIO LLC, Denver, CO (US)
Appl. No. 17/762,149
Filed by MyCardio LLC, Denver, CO (US)
PCT Filed Sep. 21, 2020, PCT No. PCT/US2020/051799
§ 371(c)(1), (2) Date Mar. 21, 2022,
PCT Pub. No. WO2021/055943, PCT Pub. Date Mar. 25, 2021.
Claims priority of provisional application 62/903,833, filed on Sep. 21, 2019.
Prior Publication US 2022/0386946 A1, Dec. 8, 2022
Int. Cl. A61B 5/00 (2006.01); A61B 5/0205 (2006.01); G16H 10/60 (2018.01)
CPC A61B 5/4812 (2013.01) [A61B 5/0205 (2013.01); A61B 5/7278 (2013.01); A61B 5/7289 (2013.01); G16H 10/60 (2018.01)] 12 Claims
OG exemplary drawing
 
1. A computer-implemented method comprising:
computing cardiopulmonary coupling data spanning a sleep period for a person;
classifying an epoch in the sleep period as a very-low frequency coupling (vLFC) epoch based on the cardiopulmonary coupling data;
accessing pseudo-actigraphy data for the person corresponding to the vLFC epoch, wherein the pseudo-actigraphy data is based on physiological measurements of the person and is not based on actigraphy measurements, and wherein the physiological measurements, on which the pseudo-actigraphy data is based, are separate and different from the cardiopulmonary coupling data;
determining, based on the pseudo-actigraphy data corresponding to the vLFC epoch, between a REM epoch and a wake epoch to distinguish between a REM epoch and a wake epoch for the vLFC epoch; and
designating the vLFC epoch as a REM epoch or as a wake epoch based on a result of the determining.