US 12,257,066 B2
Method and apparatus to measure bone hemodynamics and discriminate healthy from diseased bone, and open reduction internal fixation implant with integrated optical sensors
Jonathan Thomas Elliott, Meriden, NH (US); Ida Leah Gitajn, Hanover, NH (US); Shudong Jiang, Hanover, NH (US); and Brian Pogue, Hanover, NH (US)
Assigned to THE TRUSTEES OF DARTMOUTH COLLEGE, Hanover, NH (US)
Appl. No. 17/290,991
Filed by THE TRUSTEES OF DARTMOUTH COLLEGE, Hanover, NH (US)
PCT Filed Nov. 1, 2019, PCT No. PCT/US2019/059487
§ 371(c)(1), (2) Date May 3, 2021,
PCT Pub. No. WO2020/092968, PCT Pub. Date May 7, 2020.
Claims priority of provisional application 62/755,067, filed on Nov. 2, 2018.
Prior Publication US 2022/0096000 A1, Mar. 31, 2022
Int. Cl. A61B 17/80 (2006.01); A61B 5/00 (2006.01)
CPC A61B 5/4504 (2013.01) [A61B 5/0071 (2013.01); A61B 5/4851 (2013.01); A61B 17/80 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A system comprising:
an open surgical reduction with internal fixation (ORIF) implant for treatment of fractures, the implant comprising:
a rigid plate or rod and an integrated electronics module,
the integrated electronics module comprising at least two optical sensors adapted to sense fluorescent emissions, at least one fluorescent stimulus wavelength light source, and a near-field digital radio; the optical sensors coupled through at least one analog to digital converter to the near-field digital radio,
wherein the rigid plate or rod of the implant comprises polyethylene terephthalate glycol-modified (PETG) or ultra-high molecular weight polyethylene (UHMWPE);
a near-field radio exciter-reader adapted to power and receive data from the implant, a processor, and a memory coupled to the processor; where the processor is configured by machine readable code in the memory to obtain a sequence of readings of the optical sensors from the implant and to fit the sequence of readings to a model of perfusion of bone.