US 12,257,047 B2
Concentration measurement device and concentration measurement method
Tsuyoshi Kamada, Hamamatsu (JP); Takeo Ozaki, Hamamatsu (JP); and Wataru Kamo, Hamamatsu (JP)
Assigned to HAMAMATSU PHOTONICS K.K., Hamamatsu (JP)
Appl. No. 17/293,061
Filed by HAMAMATSU PHOTONICS K.K., Hamamatsu (JP)
PCT Filed Oct. 30, 2019, PCT No. PCT/JP2019/042666
§ 371(c)(1), (2) Date May 12, 2021,
PCT Pub. No. WO2020/121675, PCT Pub. Date Jun. 18, 2020.
Claims priority of application No. 2018-230876 (JP), filed on Dec. 10, 2018.
Prior Publication US 2021/0401335 A1, Dec. 30, 2021
Int. Cl. A61B 5/1455 (2006.01); A61B 5/00 (2006.01); A61B 5/08 (2006.01)
CPC A61B 5/14551 (2013.01) [A61B 5/0816 (2013.01); A61B 5/7225 (2013.01); A61B 5/742 (2013.01)] 4 Claims
OG exemplary drawing
 
3. A concentration measurement method comprising:
inputting measurement light to a measurement target portion;
detecting the measurement light propagated inside the measurement target portion, and generating a detection signal according to an intensity of the measurement light;
performing a calculation of obtaining hemoglobin-related information including at least one of a temporal relative change amount of a total hemoglobin concentration, a temporal relative change amount of an oxygenated hemoglobin concentration, a temporal relative change amount of a deoxygenated hemoglobin concentration, and a hemoglobin oxygen saturation based on the detection signal; and
before the calculation, receiving a signal related to a set respiratory rate from a ventilator used in combination and connected in a wired or wireless manner, wherein
in the calculation, filter processing of extracting a component derived from respiration among frequency components included in the detection signal, the hemoglobin-related information, or a numerical value appearing in a calculation process of the hemoglobin-related information is performed for obtaining the hemoglobin-related information in a vein of the measurement target portion,
the set respiratory rate of the ventilator is included in a passband of a band-pass filter in the filter processing, and
in the calculation, the passband of the band-pass filter in the filter processing is determined according to the set respiratory rate such that the set respiratory rate becomes a center frequency of the passband.