US 12,256,979 B2
Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
Denise Zarins, Los Gatos, CA (US); Benjamin J. Clark, Redwood City, CA (US); Nicolas Zadno, Fremont, CA (US); Hanson S. Gifford, III, Woodside, CA (US); and Erik Thai, Mountain View, CA (US)
Assigned to Medtronic Ireland Manufacturing Unlimited Company, Dublin (IE)
Filed by Medtronic Ireland Manufacturing Unlimited Company, Dublin (IE)
Filed on Aug. 17, 2021, as Appl. No. 17/404,895.
Application 14/574,262 is a division of application No. 13/007,370, filed on Jan. 14, 2011, granted, now 8,958,871, issued on Feb. 17, 2015.
Application 17/404,895 is a continuation of application No. 16/048,510, filed on Jul. 30, 2018, abandoned.
Application 16/048,510 is a continuation of application No. 15/132,445, filed on Apr. 19, 2016, granted, now 10,039,596, issued on Aug. 7, 2018.
Application 15/132,445 is a continuation of application No. 14/574,262, filed on Dec. 17, 2014, granted, now 9,364,280, issued on Jun. 14, 2016.
Application 13/007,370 is a continuation of application No. 12/616,708, filed on Nov. 11, 2009, granted, now 7,873,417, issued on Jan. 18, 2011.
Application 12/616,708 is a continuation of application No. 11/363,867, filed on Feb. 27, 2006, granted, now 7,620,451, issued on Nov. 17, 2009.
Claims priority of provisional application 60/813,589, filed on Dec. 29, 2005.
Prior Publication US 2021/0369334 A1, Dec. 2, 2021
Int. Cl. A61N 1/36 (2006.01); A61B 18/12 (2006.01); A61B 18/14 (2006.01); A61M 5/14 (2006.01); A61M 37/00 (2006.01); A61N 1/05 (2006.01); A61N 1/32 (2006.01); A61B 18/00 (2006.01)
CPC A61B 18/1477 (2013.01) [A61B 18/1206 (2013.01); A61M 5/14 (2013.01); A61M 37/00 (2013.01); A61N 1/05 (2013.01); A61N 1/0514 (2013.01); A61N 1/0551 (2013.01); A61N 1/321 (2013.01); A61N 1/327 (2013.01); A61N 1/36007 (2013.01); A61B 2018/0022 (2013.01); A61B 2018/00267 (2013.01); A61B 2018/00404 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00505 (2013.01); A61B 2018/00613 (2013.01); A61B 2018/126 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An apparatus for neuromodulation of a human patient, the apparatus comprising:
a catheter defining a lumen extending along the catheter to a lumen outlet; and
a neuromodulation assembly movable relative to the catheter within the lumen, the neuromodulation assembly comprising an outer member and a neuromodulation element,
wherein the outer member is configured to extend, in a treatment configuration of the apparatus while the catheter and the outer member are positioned in an interior of a blood vessel, through the lumen outlet at least to a wall of the blood vessel, and
wherein an end portion of the neuromodulation element is configured to, in the treatment configuration of the apparatus, extend beyond an end of the outer member and the lumen outlet, and through the wall of the blood vessel.