US 12,256,759 B2
Methods for the reduction of methane production in ruminants
Abed Chaudhury, Orange (AU); Karen Paco, St. Paul, MN (US); Michael Anthony Ayliffe, Canberra (AU); Thomas David Loan, Canberra (AU); Ming Luo, Canberra (AU); and Tristan Yang, St. Paul, MN (US)
Assigned to Loam Bio Pty Ltd, Orange (AU)
Appl. No. 18/291,870
Filed by Loam Bio Pty Ltd, Orange (AU)
PCT Filed Aug. 2, 2022, PCT No. PCT/US2022/039095
§ 371(c)(1), (2) Date Jan. 24, 2024,
PCT Pub. No. WO2023/009899, PCT Pub. Date Feb. 2, 2023.
Claims priority of application No. 2021902354 (AU), filed on Jul. 30, 2021.
Prior Publication US 2024/0260608 A1, Aug. 8, 2024
Int. Cl. A23K 10/16 (2016.01); A23K 20/189 (2016.01); A23K 50/10 (2016.01); A61K 36/062 (2006.01); A61K 38/44 (2006.01); C12N 1/14 (2006.01); C12N 9/08 (2006.01); C12R 1/645 (2006.01)
CPC A23K 10/16 (2016.05) [A23K 20/189 (2016.05); A23K 50/10 (2016.05); A61K 36/062 (2013.01); A61K 38/44 (2013.01); C12N 1/145 (2021.05); C12N 9/0065 (2013.01); C12Y 111/01018 (2013.01); C12R 2001/645 (2021.05)] 5 Claims
 
1. A method for reducing methane emissions from a ruminant,
the method comprising administering to the ruminant bromoform produced by a composition comprising:
bromide, and
a vanadium-dependent haloperoxidase (VHPO) comprising SEQ ID NO: 2;
thereby reducing methane emissions in the ruminant relative to a ruminant not administered bromoform produced by the composition.