CPC G01J 3/0272 (2013.01) [G01J 3/0256 (2013.01); G01J 3/4412 (2013.01); G01N 21/658 (2013.01); G01N 33/523 (2013.01); G01N 33/6812 (2013.01)] | 15 Claims |
1. A method for fabrication of a gold nanoporous anodic aluminum oxide (NAAO) substrate used in coordination with a handheld Surface-Enhanced Raman Spectroscopy (SERS) device for detecting phenylalanine (Phe) in a sample collected from a subject, the method comprising:
forming a three-phase system on top of a multilayered nanoporous aluminum layer of the gold NAAO substrate; wherein the three-phase system comprises an air phase, a water phase, and an oil phase; and
injecting a cosolvent solution into the three-phase system, wherein the cosolvent solution comprises gold nanoparticles; and
drying the gold NAAO substrate by evaporating the water phase and the oil phase;
wherein the gold NAAO substrate formed is used in coordination with the handheld SERS device.
|