	US 11,932,894 B2
	Method for producing albicanol and/or drimenol
Michel Schalk, Satigny (CH); Pauline Anziani, Satigny (CH); Christian Goerner, Satigny (CH); and Daniel Solis Escalante, Satigny (CH)
Assigned to FIRMENICH SA, Satigny (CH)
Filed by FIRMENICH SA, Satigny (CH)
Filed on Feb. 16, 2022, as Appl. No. 17/673,465.
Application 17/673,465 is a division of application No. 16/618,737, granted, now 11,293,037, previously published as PCT/EP2018/064344, filed on May 31, 2018.
Claims priority of application No. 17174399 (EP), filed on Jun. 2, 2017.
Prior Publication US 2022/0186265 A1, Jun. 16, 2022 Prior Publication US 2023/0148463 A9, May 11, 2023
Int. Cl. C12P 7/02 (2006.01); C12N 9/88 (2006.01)

CPC C12P 7/02 (2013.01) [C12N 9/88 (2013.01); C12Y 402/03 (2013.01)]

2 Claims

1. An isolated polypeptide comprising a Haloacid dehalogenase (HAD)-like hydrolase domain and having bifunctional terpene synthase activity comprising

a) an amino acid sequence having at least 90%, 95%, 96%, 97%, 98% or 99% sequence identity to SEQ ID NO: 1 or SEQ ID NO: 5, wherein the amino acid sequence is a variant of SEQ ID NO: 1 or SEQ ID NO: 5 and does not have 100% sequence identity to SEQ ID NO: 1 or SEQ ID NO: 5;

b) a sequence as set forth in SEQ ID NO: 53, SEQ ID NO: 54, or SEQ ID NO: 55; and

c) a sequence as set forth in SEQ ID NO: 56, SEQ ID NO: 57, or SEQ ID NO: 58.