CPC C07K 16/2869 (2013.01) [A61K 35/17 (2013.01); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70578 (2013.01); C07K 14/71 (2013.01); C07K 16/3076 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01)] | 24 Claims |
1. An antibody or antigen binding fragment that specifically binds mesothelin, comprising:
a single domain antibody (sdAb) comprising a complementarity determining region 1 (CDR1), a CDR2 and a CDR3 having the polypeptide sequences of:
a. SEQ ID NOs:66, 134, and 202, respectively;
b. SEQ ID NOs:67, 135, and 203, respectively; or
c. SEQ ID NOs:34, 102, and 170, respectively.
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