CPC C07D 491/16 (2013.01) [A61P 31/14 (2018.01)] | 10 Claims |
1. A lycorine derivative of General Formula (I), or a pharmaceutically acceptable salt thereof:
wherein X is O, S or CH2; n=0, 1, 2, 3, 4, or 5; Ar is a C6-10 aromatic ring or a C3-10 heteroaromatic ring; R is optionally mono-substituted, di-substituted or multi-substituted, and R is independently selected from hydrogen, halogen, nitro, amino, hydroxy, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylamino, C6-10 aryl, C1-6 alkynyl, C1-6 alkenyl, C3-6 cycloalkyl, C3-6 heterocycloalkyl, C1-6 alkylacyl, and C6-10 arylacyl, where the C3-10 heteroaromatic ring contains a heteroatom, and the heteroatom is selected from N, O, and S.
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