US 11,931,954 B2
Method of producing a test body for diffusion tensor imaging
Aleksandr Ovsianikov, Vienna (AT); Peter Gruber, Vienna (AT); Christian Windischberger, Vienna (AT); and Zoltan Nagy, Zurich (CH)
Assigned to TECHNISCHE UNIVERSITAT WIEN, Vienna (AT)
Appl. No. 17/415,416
Filed by Technische Universität Wien, Vienna (AT); and Medizinische Universität Wien, Vienna (AT)
PCT Filed Dec. 20, 2019, PCT No. PCT/AT2019/000035
§ 371(c)(1), (2) Date Jun. 17, 2021,
PCT Pub. No. WO2020/124106, PCT Pub. Date Jun. 25, 2020.
Claims priority of application No. 18000986 (EP), filed on Dec. 20, 2018.
Prior Publication US 2022/0111581 A1, Apr. 14, 2022
Int. Cl. B29C 64/129 (2017.01); B33Y 10/00 (2015.01); B33Y 70/00 (2020.01); G01R 33/563 (2006.01); G01R 33/58 (2006.01); G03F 7/029 (2006.01); G03F 7/20 (2006.01); B29K 105/00 (2006.01); B29L 31/40 (2006.01)
CPC B29C 64/129 (2017.08) [B33Y 10/00 (2014.12); B33Y 70/00 (2014.12); G01R 33/56341 (2013.01); G01R 33/58 (2013.01); G03F 7/029 (2013.01); G03F 7/2053 (2013.01); B29K 2105/0005 (2013.01); B29L 2031/40 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method of producing a test body for diffusion tensor imaging, which comprises a plurality of channels in a structuring material, the channels having a maximum cross-section of 625 μm2, the method comprising:
creating a virtual model of the test body,
feeding the virtual model to a structuring device,
the structuring device producing the test body by means of a 3D printing-based structuring process, the structuring process being designed as a multi photon lithography process wherein the structuring process comprises irradiating the structuring material containing a photosensitizer or photoinitiator in a location-selective manner, wherein radiation is successively focused on focal points lying within the structuring material, resulting in that in each case a volume element of the structuring material located in a focal point is subjected to a change in state by means of a photochemical reaction as a result of multi photon absorption and in that the plurality of channels is created in the structuring material.