CPC A61K 31/444 (2013.01) [A61K 31/551 (2013.01); A61P 35/02 (2018.01)] | 5 Claims |
1. A method of treating inv(16) leukemia in a subject comprising the steps of:
administering to the subject a therapeutically effective combination of:
a) a compound of formula (1a)
or a pharmaceutically acceptable salt thereof; and
b) a BRD4 inhibitor selected from JQ1 and a pharmaceutically acceptable salt thereof,
wherein the therapeutically effective combination of the compound of formula (1a) and the BRD4 inhibitor synergistically inhibits proliferation of inv(16) leukemia cells.
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