CPC A61K 31/202 (2013.01) [A61K 31/192 (2013.01); A61K 35/74 (2013.01); A61K 36/54 (2013.01); A61K 36/75 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61P 27/04 (2018.01)] | 19 Claims |
1. A method for treating the symptoms associated with dry eye comprising the step of administering a composition comprising:
i) a safe and effective amount of a compound and/or extract having retinol-like properties and/or benefits for use in treating dry eye selected from one or more of: botanical extracts from plants of the genus Acronychia, Licaria, Calendula and/or Trigonella; bacterial extracts of the genus Actinomyces; and compounds of Formula (I):
![]() wherein—
the dotted lines represent simple or double bound;
R1 represent an H, a carbonated chain, linear, cyclic, or branched, saturated or unsaturated, comprising from 1 to 20 carbon atoms;
R2 represent a carbonated chain, linear, cyclic ringed, or branched, saturated or unsaturated, comprising from 1 to 20 carbon atoms; preferably a methyl (—CH3) or methylene (═CH2) moiety;
a represent a carbonated chain, linear, ringed, or branched, saturated or unsaturated, comprising from 1 to 20 carbon atoms; and
ii) optionally, an ophthalmologically acceptable carrier.
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