	US 12,252,714 B2
	Halogenation of complex organic compounds
David H. Sherman, Ann Arbor, MI (US); Amy E. Fraley, Ann Arbor, MI (US); and Ashootosh Tripathi, Ypsilanti, MI (US)
Assigned to REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US)
Filed by REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US)
Filed on May 15, 2023, as Appl. No. 18/317,683.
Application 18/317,683 is a division of application No. 17/228,211, filed on Apr. 12, 2021, granted, now 11,692,176.
Application 17/228,211 is a division of application No. 16/516,102, filed on Jul. 18, 2019, granted, now 11,008,553.
Claims priority of provisional application 62/700,152, filed on Jul. 18, 2018.
Prior Publication US 2024/0043815 A1, Feb. 8, 2024
Int. Cl. C12N 9/02 (2006.01); A61K 31/4995 (2006.01); C12P 17/18 (2006.01)

CPC C12N 9/0071 (2013.01) [A61K 31/4995 (2013.01); C12P 17/182 (2013.01)]

3 Claims

1. A method of modulating a Ca²⁺ signaling pathway in a cell of a mammal comprising administering an effective amount of a halogenated complex organic compound to the mammal to modulate the Ca2+ signaling pathway, wherein the halogenated complex organic compound is isomalbrancheamide D.