	US 12,252,710 B2
	Cationic dendrimers for the culture of adherent cells
Timothy E. Kennedy, Montreal (CA); Jean-Pierre Clement, Montreal (CA); and Laila Al-Alwan, Montreal (CA)
Assigned to THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, Montréal (CA)
Filed by THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, Montréal (CA)
Filed on Apr. 19, 2022, as Appl. No. 17/724,038.
Claims priority of provisional application 63/219,083, filed on Jul. 7, 2021.
Prior Publication US 2023/0016634 A1, Jan. 19, 2023
Int. Cl. C12N 5/0793 (2010.01); C12M 1/12 (2006.01); C12N 5/079 (2010.01)

CPC C12N 5/0619 (2013.01) [C12M 25/04 (2013.01); C12N 5/0622 (2013.01); C12N 2500/32 (2013.01); C12N 2500/38 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/119 (2013.01); C12N 2501/13 (2013.01); C12N 2506/45 (2013.01); C12N 2533/40 (2013.01); C12N 2533/52 (2013.01); C12N 2535/10 (2013.01)]

14 Claims

1. A cell or tissue culture system comprising (i) a solid support for the culture of adherent cells or adherent tissues and (ii) a plurality of cationic polyglycerol dendrimers associated to the surface of the solid support via electrostatic interactions, wherein each of the cationic polyglycerol dendrimer includes one or more functional amine group and is protonated at physiological pH.