| CPC A61M 31/00 (2013.01) [A61F 11/08 (2013.01); A61M 5/30 (2013.01); A61F 11/085 (2022.01); A61M 2205/3317 (2013.01); A61M 2205/3327 (2013.01); A61M 2205/3375 (2013.01); A61M 2205/75 (2013.01); A61M 2210/0618 (2013.01); A61M 2210/0662 (2013.01); G10K 11/1752 (2020.05); H04R 1/1016 (2013.01); H04R 25/652 (2013.01)] | 17 Claims |

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1. A plug for insertion into a nose or ear of a subject, comprising:
a body adapted to fit into a nostril or ear canal of the subject, the body comprising a first end arranged to face inward and a second end arranged to face outward during use, wherein the body comprises a compressible, resilient foam material adapted to absorb liquid;
a hollow tubular member disposed inside the body and extending substantially an entire length of the body and comprising a tubular portion having a first opening facing inwardly and a second opening facing outward during use, the hollow tubular member being arranged to provide fluid communication between the first and second openings;
wherein the hollow tubular member further comprises a cup-shaped collar arranged on an external surface of the tubular portion and extending radially outward from the tubular portion, wherein a rim of the collar, defined by a radially outermost surface of the collar, is disposed inside the body in contact with an inner wall of the body at the second end of the body, wherein a substantially concave side of the collar faces towards the first end of the body; and
wherein the second opening of the hollow tubular member is adapted to receive a tip of a syringe for injection of a fluid therapeutic agent through the hollow tubular member.
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9. A kit comprising at least one plug for insertion into the nose or ear of a subject and at least one syringe pre-filled with a fluid to be injected into the nostril or ear canal of the subject through the plug, the plug comprising:
a body adapted to fit into a nostril or ear canal of the subject, the body comprising a first end arranged to face inward and a second end arranged to face outward during use, wherein the body comprises a compressible, resilient foam material adapted to absorb liquid;
a hollow tubular member disposed inside the body and extending substantially an entire length of the body and comprising a tubular portion having a first opening facing inwardly and a second opening facing outward during use, the hollow tubular member being arranged to provide fluid communication between the first and second openings;
wherein the hollow tubular member further comprises a cup-shaped collar arranged on an external surface of the tubular portion and extending radially outward from the tubular portion, wherein a rim of the collar, defined by a radially outermost surface of the collar, is disposed inside the body in contact with an inner wall of the body at the second end of the body, wherein a substantially concave side of the collar faces towards the first end of the body; and
wherein the second opening of the hollow tubular member is adapted to receive a tip of the syringe for injection of a fluid therapeutic agent through the hollow tubular member.
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