US 12,251,428 B2
Hydrogel composition, hydrogel biomedical material, method for facilitating regeneration of bone and manufacturing method of hydrogel composition
Cherng-Jyh Ke, Taichung (TW); Feng-Huei Lin, Taichung (TW); Chun-Hsu Yao, Taichung (TW); Jui-Sheng Sun, Taichung (TW); and Ching-Yun Chen, Taichung (TW)
Assigned to CHINA MEDICAL UNIVERSITY, Taichung (TW)
Filed by China Medical University, Taichung (TW)
Filed on Jun. 30, 2022, as Appl. No. 17/854,229.
Claims priority of provisional application 63/217,377, filed on Jul. 1, 2021.
Prior Publication US 2023/0012279 A1, Jan. 12, 2023
Int. Cl. A61K 38/45 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 31/728 (2006.01); A61K 35/16 (2015.01); A61K 35/19 (2015.01); A61K 38/36 (2006.01); A61K 47/02 (2006.01); A61K 47/18 (2017.01); A61K 47/34 (2017.01); A61K 47/36 (2006.01); A61K 47/42 (2017.01); A61K 47/69 (2017.01)
CPC A61K 38/45 (2013.01) [A61K 9/0024 (2013.01); A61K 9/06 (2013.01); A61K 31/728 (2013.01); A61K 35/16 (2013.01); A61K 35/19 (2013.01); A61K 38/36 (2013.01); A61K 47/02 (2013.01); A61K 47/183 (2013.01); A61K 47/34 (2013.01); A61K 47/36 (2013.01); A61K 47/42 (2013.01); A61K 47/6903 (2017.08)] 3 Claims
OG exemplary drawing
 
1. A hydrogel composition, comprising:
a first deionized water;
a gel powder comprising gelatin and alginic acid;
a transglutaminase mixture; and
a hyaluronic acid powder;
wherein the first deionized water, the gel powder, the transglutaminase mixture and the hyaluronic acid powder are evenly mixed;
wherein based on the hydrogel composition being 100 wt %, the first deionized water is 95 wt % to 98.46 wt %, the gel powder is 1 wt % to 3 wt %, the transglutaminase mixture is 0.04 wt % to 0.15 wt %, and the hyaluronic acid powder is 0.5 wt % to 1.5 wt %.