US 12,251,336 B2
Expandable drug delivery devices and methods of use
Bradley G. Bachelder, South San Francisco, CA (US); Randolph E. Campbell, Redwood City, CA (US); Darren Doud, Los Altos, CA (US); Signe Erickson, South San Francisco, CA (US); and Kevin W. Sacherman, Palo Alto, CA (US)
Assigned to ForSight Vision4, Inc., South San Francisco, CA (US)
Filed by ForSight Vision4, Inc., South San Francisco, CA (US)
Filed on Aug. 3, 2021, as Appl. No. 17/393,059.
Application 17/393,059 is a continuation of application No. 16/671,749, filed on Nov. 1, 2019, granted, now 11,110,001.
Application 16/671,749 is a continuation of application No. 14/937,754, filed on Nov. 10, 2015, granted, now 10,500,091, issued on Dec. 10, 2019.
Claims priority of provisional application 62/077,829, filed on Nov. 10, 2014.
Prior Publication US 2022/0087863 A1, Mar. 24, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 9/00 (2006.01); A61K 9/00 (2006.01)
CPC A61F 9/0017 (2013.01) [A61K 9/0051 (2013.01); A61F 2210/0014 (2013.01); A61F 2210/0061 (2013.01); A61F 2250/001 (2013.01); A61F 2250/0068 (2013.01); A61F 2250/0069 (2013.01)] 25 Claims
OG exemplary drawing
 
1. A drug delivery device configured to be at least partially implanted in an eye, the device comprising:
a retention structure positioned near a proximal end region of the device;
a porous drug release element positioned in fluid communication with an outlet of the device;
an elongated core element having a longitudinal axis extending from a proximal end of the elongated core element to a distal end of the elongated core element; and
a reservoir wall positioned around and eccentric to the longitudinal axis of the elongated core element, the reservoir wall defining a reservoir volume configured to contain one or more therapeutic agents, the reservoir volume in fluid communication with the outlet through the porous drug release element,
wherein the reservoir wall is configured to transition from an insertion configuration having a first three-dimensional shape to a deployed configuration having a second three-dimensional shape such that the second three-dimensional shape is eccentrically positioned relative to the longitudinal axis of the elongated core element.