| CPC A61F 7/12 (2013.01) [A61B 5/1101 (2013.01); A61B 5/1107 (2013.01); A61B 5/1126 (2013.01); A61B 5/24 (2021.01); A61B 5/316 (2021.01); A61B 5/389 (2021.01); A61B 5/4052 (2013.01); A61B 5/4836 (2013.01); A61B 5/725 (2013.01); A61B 5/746 (2013.01); A61F 7/10 (2013.01); A61N 2/006 (2013.01); A61N 2/02 (2013.01); A61B 5/024 (2013.01); A61B 5/037 (2013.01); A61B 5/0816 (2013.01); A61B 5/14542 (2013.01); A61B 5/4866 (2013.01); A61B 5/6823 (2013.01); A61B 5/6824 (2013.01); A61F 2007/0054 (2013.01); A61F 2007/0056 (2013.01); A61F 2007/0093 (2013.01); A61F 2007/126 (2013.01); A61N 1/36003 (2013.01); A61N 1/36014 (2013.01); A61N 1/36017 (2013.01); A61N 1/36025 (2013.01)] | 20 Claims |

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1. A system for cooling a body of a subject, the system comprising:
a cooling device configured for actively cooling a subject;
a sensor configured to obtain physiological data from a subject undergoing the active cooling, the physiological data comprising breathing rate, oxygen consumption, or oxygen saturation of arterial blood or venous blood supply to a specific area of the subject; and
a controller configured to perform operations comprising:
based on the physiological data, identifying prior to an onset of shivering a portion of the physiological data that indicates preshivering of the subject;
based on the portion of the physiological data that indicates preshivering of the subject prior to the onset of shivering, controlling the active cooling of the subject by the cooling device, wherein controlling the active cooling comprises automatically initiating a response based on the portion of the physiological data that indicates preshivering;
determining a continued presence of preshivering for the subject after the response has been initiated; and
periodically adjusting the response based upon determining the continued presence of preshivering for the subject after the response.
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